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Dansk

Information for those who had one dose of AstraZeneca followed by a dose of one of the mRNA vaccines

If you were cross-vaccinated with the vaccine from AstraZeneca and then an mRNA vaccine, the Danish Health Authority recommends that you accept the offer of a booster dose with an mRNA vaccine when you receive an invitation.

In April 2021, the Danish Health Authority decided to continue the Danish vaccination programme without the COVID-19 vaccine from AstraZeneca (Vaxzevria). By then, about 145,000 citizens had been vaccinated with this vaccine, but only a few had received the second dose.

Since May, the Danish Health Authority has recommended that these individuals receive the 2nd dose with a dose of an mRNA vaccine – either Comirnaty© (Pfizer-BioNTech) or Spikevax® (Moderna) – approximately 12 weeks after the initial dose of the vaccine from AstraZeneca.

Getting your initial COVID-19 vaccine from one manufacturer and then your second dose or booster from a different manufacturer is called ‘mixing and matching’ or cross vaccination. At this time, we recommend that you accept a booster dose with an mRNA vaccine.

Everyone aged 18 and over can get the booster dose 140 days (about 4,5 months) after you received the 2nd vaccine dose. 

We recommend that you accept the offer of a 3rd dose as soon as possible after the 140 days have elapsed.

Please note that you do not have to wait to get an invitation in your e-Boks. You can get vaccinated as soon as 140 days have passed since your second vaccine dose.

 

3rd booster dose

1. Are the vaccines approved for use as a 3rd booster dose?

At the present moment, the European Medicines Agency  (EMA) has yet to approve the use of a COVID-19 mRNA vaccine as a booster for people who have received one dose of AstraZeneca and one dose of an mRNA vaccine. However, the Danish Health Authority assesses that this approach does not increase the risk of severe side effects, although you may still experience mild side effects such as pain at the injection site,  fatigue, muscle pain, headache and a slight fever. These are all known side effects you may have experienced after your initial vaccination series; however, they may be more pronounced after the booster dose.

2. What should I do if I am cross-vaccinated and would like a booster dose?

If you wish to get vaccinated, you can book a time slot at a vaccination centre on vacciner.dk.

At the vaccination centre:

As this is an offer that the EMA has not approved, vaccination is carried out in a slightly different way than usually:

  • You will be met by a poster telling you to inform the staff that you are cross-vaccinated.
  • You will be provided with information material on the vaccination of cross-vaccinated people, which you will have the opportunity to read at the vaccination centre.
  • The vaccinator will then talk to you about the vaccination itself – including efficacy and side effects.
  • You must confirm that you consent to the procedure based on the information you have been given.
  • You can now get vaccinated.
  • Like everyone else who gets vaccinated, you must remain seated for observation until 15 minutes have elapsed after you have been vaccinated.

3. Is it safe to get the booster dose? Can I expect worse or different side effects?

The Danish Health Authority assesses that there will be no risk of severe side effects from receiving a booster dose with an mRNA vaccine when you have previously received your initial dose with the AstraZeneca vaccine and the 2nd with an mRNA vaccine. You may experience known and mild side effects such as pain at the injection site,  fatigue, muscle pain, headache and a slight fever. These are all known side effects you may have experienced after your initial vaccination series; however, they may be more pronounced after the booster dose.

4. Which type of vaccine will I be given?

You will be given the same type of vaccine you received when you got your 2nd dose. For example, if your 2nd dose was with the COVID-19 vaccine from Moderna, your top-up booster will also be with the Moderna vaccine.

5. Can I get my booster dose sooner?

The Danish Health Authority recommends that you hold off on getting the 3rd booster dose until 4,5 months have passed since your 2nd vaccine dose and you receive the offer of revaccination. 

However, you can book an appointment for the booster dose even sooner. We have opened up the possibility of early revaccination because some countries do not recognise travellers with mixed vaccine doses as being fully vaccinated. However, if you have no urgent need to travel, we recommend that you wait for the required length of time – 4,5 months, – before getting your booster dose.

6. Am I then guaranteed entry into other countries?

Entry requirements in other countries vary and may change at a moments notice. Each country sets and enforces its own entry rules and restrictions, including whether they recognise your country’s vaccine programme. Therefore, you should always stay updated on the entry rule of the country that you plan to visit or transit in.

Updated 25 JAN 2022